RESEARCH FOR PREPARATION OF HERBAL TEA FROM Ficus pumila L. TO SUPPORTING TREATMENT OSTEOARTHRITIS

Abstract

In this study, kaempferol compound (3,4′,5,7-tetrahydroxyflavone) was found in the extract from Ficus pumila L. collected in Trung Khanh district, Cao Bang province. Kaempferol is a compound with anti-inflammatory, antioxidant, anti-cancer, antidiabetic and neuroprotective activities. On that basis, herbal tea is prepared from the ethanol-water extract of the Ficus pumila L. species combined with Smilax glabra Roxb - a medicine with diverse biological activities that helps reduce rheumatism and detoxify, reduces pain and inflammation, enhances tendon strength and support in osteoarthritis treatment. The medicinal substance kaempferol in the herbal tea product was quantified by using high-performance chromatography technique, with a content of about 98.3 ± 2.01 mg/g. The toxicity of the herbal tea product was surveyed on zebrafish embryos according to guidelines of OECD 236 organisation, the results show that the product is none toxic. The herbal tea was determined with physicochemical criteria such as moisture of 3.22% and ash level of 11.28%, meeting the requirements according to TCVN 9739:2013 - National standard for Instant tea in solid form